ATP8B1 Deficiency Disrupts the Bile Canalicular Membrane Bilayer Structure in Hepatocytes, But FXR Expression and Activity Are Maintained

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

Tony Yeung, Gary E. Gilbert, Jialan Shi et al. · Science · 2008 · 1.1K citations

Life Sciences, Biochemistry, Cell Biology +17

A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis

Laura N. Bull, Michiel J. T. van Eijk, Ludmila Pawlikowska et al. · Nature Genetics · 1998 · 738 citations

Life Sciences, Genetics, Molecular Genetics +12

Genetic and morphological findings in progressive familial intrahepatic cholestasis (Byler disease [PFIC-1] and Byler syndrome): Evidence for heterogeneity

L Bull, Victoria Carlton, N L Stricker et al. · Hepatology · 1997 · 278 citations

Medicine, Genetics, Pathology +17

ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity

Coen C. Paulusma, Dineke E. Folmer, Kam S. Ho‐Mok et al. · Hepatology · 2007 · 245 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport

Coen C. Paulusma, Annemiek Groen, Cindy Kunne et al. · Hepatology · 2006 · 231 citations · Full text

Life Sciences, Biochemistry, Genetics +17