Studies on an acidic glycoprotein-containing fraction isolated from guinea-pig serum

Abstract

Although many of the proteins found in serum contain carbohydrate, there has until recently been relatively little information concerning the nature of the carbohydrate prosthetic groups which such proteins contain, and little is yet known about the metabolism of these glycoproteins. Most of the work on characterization and structure hitherto reported has been carried out on glycoproteins isolated from the serum of larger mammals. Because advantages result from the use of a smaller animal in studies of biosynthesis, an in- vestigation has been begun of the characteristics and structure of certain glycoproteins present in the serum of the guinea pig in order to lay a basis for subsequent work on their biosynthesis.