Discovery and structure–activity relationship of 2,6-disubstituted pyrazines, potent and selective inhibitors of protein kinase CK2

The Copper-Catalyzed <i>N</i>-Arylation of Indoles

Jon C. Antilla, Artis Klapars, Stephen L. Buchwald · Journal of the American Chemical Society · 2002 · 550 citations

Cross-coupling Reaction, Engineering, Aryl Bromide +10

Protein kinase CK2 in mammary gland tumorigenesis

Esther Landesman‐Bollag, Raphaëlle Romieu‐Mourez, Diane H. Song et al. · Oncogene · 2001 · 295 citations

Receptor Tyrosine Kinase, Mammary Gland, Breast Cancer +5

Discovery and SAR of 5-(3-Chlorophenylamino)benzo[<i>c</i>][2,6]naphthyridine-8-carboxylic Acid (CX-4945), the First Clinical Stage Inhibitor of Protein Kinase CK2 for the Treatment of Cancer

Fabrice Pierre, Peter Chua, Sean O’Brien et al. · Journal of Medicinal Chemistry · 2010 · 295 citations · Full text

Discovery of a Potent and Selective Protein Kinase CK2 Inhibitor by High-Throughput Docking

Eric Vangrevelinghe, Kaspar Zimmermann, Joseph Schoepfer et al. · Journal of Medicinal Chemistry · 2003 · 215 citations

Molecular Docking, Medicinal Chemistry, Drug Target +15

Optimization of Protein Kinase CK2 Inhibitors Derived from 4,5,6,7-Tetrabromobenzimidazole

Mario A. Pagano, Mariola Andrzejewska, Maria Ruzzene et al. · Journal of Medicinal Chemistry · 2004 · 184 citations · Full text