Discovery and structure–activity relationship of 2,6-disubstituted pyrazines, potent and selective inhibitors of protein kinase CK2

References

Page 1

	Year	Citations
The Copper-Catalyzed <i>N</i>-Arylation of Indoles Jon C. Antilla, Artis Klapars, Stephen L. Buchwald Journal of the American Chemical Society Cross-coupling ReactionEngineeringAryl BromideOrganic ChemistryOrganometallic Catalysis	2002	550
Protein kinase CK2 in mammary gland tumorigenesis Esther Landesman‐Bollag, Raphaëlle Romieu‐Mourez, Diane H. Song, Oncogene Receptor Tyrosine KinaseMammary GlandBreast CancerMedicineCell Biology	2001	295
Discovery and SAR of 5-(3-Chlorophenylamino)benzo[<i>c</i>][2,6]naphthyridine-8-carboxylic Acid (CX-4945), the First Clinical Stage Inhibitor of Protein Kinase CK2 for the Treatment of Cancer Fabrice Pierre, Peter Chua, Sean O’Brien, Journal of Medicinal Chemistry	2010	295
Discovery of a Potent and Selective Protein Kinase CK2 Inhibitor by High-Throughput Docking Eric Vangrevelinghe, Kaspar Zimmermann, Joseph Schoepfer, Journal of Medicinal Chemistry Molecular DockingMedicinal ChemistryDrug TargetHigh-throughput DockingNovel Therapy	2003	215
Optimization of Protein Kinase CK2 Inhibitors Derived from 4,5,6,7-Tetrabromobenzimidazole Mario A. Pagano, Mariola Andrzejewska, Maria Ruzzene, Journal of Medicinal Chemistry	2004	184
Emodin, an Anthraquinone Derivative Isolated from the Rhizomes of Rheum palmatum, Selectively Inhibits the Activity of Casein Kinase II as a Competitive Inhibitor Hyungshin Yim, Lee, Yong Hee Chul Hoon Lee, Planta Medica	1999	166
Asymmetric Expression of Protein Kinase CK2 Subunits in Human Kidney Tumors G. Stalter, Stefan Siemer, E. Becht, Biochemical and Biophysical Research Communications Kidney ResearchMedicineReceptor Tyrosine KinasePathologyAsymmetric Expression	1994	163
Nuclear localization of protein kinase CK2 catalytic subunit (CK2α) is associated with poor prognostic factors in human prostate cancer Mathieu Laramas, Dominique Pasquier, Odile Filhol, European Journal of Cancer MedicinePoor Prognostic FactorsProtein KinaseProstatic DiseaseSystems Biology	2007	150
Casein Kinase II Alpha Subunit and C1-Inhibitor Are Independent Predictors of Outcome in Patients with Squamous Cell Carcinoma of the Lung Pornchai O‐charoenrat, Valerie W. Rusch, Simon G. Talbot, Clinical Cancer Research	2004	118
Protein kinase CK2: signaling and tumorigenesis in the mammary gland. Esther Landesman‐Bollag, Diane H. Song, Raphaëlle Romieu‐Mourez, PubMed	2001	111

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