Conversion of biliary system to pancreatic tissue in Hes1-deficient mice

<i>neurogenin3</i> is required for the development of the four endocrine cell lineages of the pancreas

Gérard Gradwohl, Andrée Dierich, Marianne LeMeur et al. · Proceedings of the National Academy of Sciences · 2000 · 1.4K citations

Cellular Physiology, Insulin Signaling, Secretory Granules +17

Signalling downstream of activated mammalian Notch

Sophie Jarriault, Christel Brou, Frédérique Logeat et al. · Nature · 1995 · 1.4K citations

Developmental Biology, Signal Transduction, Signaling Pathway +8

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

Linheng Li, Ian D. Krantz, Yu Deng et al. · Nature Genetics · 1997 · 1.3K citations

Mendelian Disorder, Genetic Disorder, Genetics +7

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

Takaya Oda, Abdel Elkahloun, Brian L. Pike et al. · Nature Genetics · 1997 · 1.2K citations

Mendelian Disorder, Human Jagged1 Gene, Genetic Disorder +8

Notch signalling controls pancreatic cell differentiation

Åsa Apelqvist, Hao Li, Lukas Sommer et al. · Nature · 1999 · 1.2K citations

Cell Lineage, Developmental Biology, Signal Transduction +9