Platelet-Derived Nucleotides Promote Tumor-Cell Transendothelial Migration and Metastasis via P2Y2 Receptor

Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell–mediated elimination of tumor cells

Joseph S. Palumbo, Kathryn E. Talmage, Jessica V. Massari et al. · Blood · 2004 · 990 citations · Full text

Medicine, Cancer Biology, Oncology +14

Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet α granules and differentially released

Joseph E. Italiano, Jennifer L. Richardson, Sunita Patel–Hett et al. · Blood · 2007 · 845 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Lysis of tumor cells by natural killer cells in mice is impeded by platelets.

Bernhard Nieswandt, Michael Häfner, Bernd Echtenacher et al. · PubMed · 1999 · 838 citations

Life Sciences, Immunology, Oncology +13

Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

Lubor Borsig, Richard W. Wong, James R. Feramisco et al. · Proceedings of the National Academy of Sciences · 2001 · 710 citations · Full text

Medicine, Cancer Biology, Oncology +16

Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer

Ahmed Boucharaba, Claire‐Marie Serre, Sandra Grès et al. · Journal of Clinical Investigation · 2004 · 410 citations · Full text

Medicine, Cancer Biology, Oncology +15