A New Half-Condensed Schiff Base Compound: Highly Selective and Sensitive pH-Responsive Fluorescent Sensor

Uday Saha, Koushik Dhara, Basab Chattopadhyay, Sushil Kumar Mandal, Swastik Mondal, Supriti Sen, Monika Mukherjee, Sander van Smaalen, Pabitra Chattopadhyay

Organic Letters · 2011 · 119 citations · 17 references

Concepts

Abstract

A new probe, 3-[(3-benzyloxypyridin-2-ylimino)methyl]-2-hydroxy-5-methylbenzaldehyde (1-H) behaves as a highly selective fluorescent pH sensor in a Britton-Robinson buffer at 25 °C. The pH titrations show a 250-fold increase in fluorescence intensity within the pH range of 4.2 to 8.3 with a pK(a) value of 6.63 which is valuable for studying many of the biological organelles.

References

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