COMBINATION CHEMOTHERAPY FOR METASTATIC OR LOCALLY ADVANCED GENITOURINARY SQUAMOUS CELL CARCINOMA: A PHASE II STUDY OF METHOTREXATE, CISPLATIN AND BLEOMYCIN

Abstract

Methotrexate, cisplatin and bleomycin combination chemotherapy for genitourinary squamous cell carcinoma results in a high but short lived overall response rate, and a low complete response rate with manageable toxicity. A multidisciplinary approach to achieve disease-free status may provide the best opportunity to effect survival and should be the focus of future trials.