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Extra-placental Expression of Vascular Endothelial Growth Factor Receptor-1, (Flt-1) and Soluble Flt-1 (sFlt-1), by Peripheral Blood Mononuclear Cells (PBMCs) in Normotensive and Preeclamptic Pregnant Women

Augustine Rajakumar, H.M. Michael, Premeela A. Rajakumar, Eiji Shibata, Carl A. Hubel, S. Ananth Karumanchi, Ravi Thadhani, Myles Wolf, Gail Harger, Nina Marković

Placenta · 2004 · 189 citations · 20 references

DOI

Concepts

References

20

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Sharon E. Maynard, Jiang-Yong Min, Jaime R. Merchan et al. · Journal of Clinical Investigation · 2003 · 3.9K citations · Full text

, , +22

Regulation of Human Placental Development by Oxygen Tension

Olga Genbačev, Yan Zhou, John W. Ludlow et al. · Science · 1997 · 909 citations

, , +17

Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis

Gavin Sacks, K. Studená, Ian L. Sargent et al. · American Journal of Obstetrics and Gynecology · 1998 · 831 citations

, , +11

Differential Transcriptional Regulation of the Two Vascular Endothelial Growth Factor Receptor Genes

Hans‐Peter Gerber, Fabrizio Condorelli, Jeanie Park et al. · Journal of Biological Chemistry · 1997 · 791 citations · Full text

Identification of a Natural Soluble Form of the Vascular Endothelial Growth Factor Receptor, FLT-1, and Its Heterodimerization with KDR

Richard Kendall, Guan Wang, Kenneth A. Thomas · Biochemical and Biophysical Research Communications · 1996 · 724 citations

, , +7