Biphenyl‐Based Diaminophosphine Oxides as Air‐Stable Preligands for the Nickel‐Catalyzed Kumada–Tamao–Corriu Coupling of Deactivated Aryl Chlorides, Fluorides, and Tosylates

Abstract

A cooperative couple: Cooperative bimetallic activation of CF and CO bonds gave rise to easy coupling with aryl fluorides and tosylates. Novel air- and moisture-stable diaminophosphine oxides derived from 1,1′-biphenyl-2,2′-diamine proved to be versatile preligands for the nickel-catalyzed cross-coupling of aryl Grignard reagents with a variety of deactivated aryl chlorides, fluorides, and tosylates (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.