Neurofibromatosis-1 Regulates Neuronal and Glial Cell Differentiation from Neuroglial Progenitors In Vivo by Both cAMP- and Ras-Dependent Mechanisms

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Shankar Srinivas, Tomoko Watanabe, Chyuan‐Sheng Lin et al. · BMC Developmental Biology · 2001 · 3.2K citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

Leisa Johnson, Kim L. Mercer, Doron C. Greenbaum et al. · Nature · 2001 · 1.2K citations

Medicine, Molecular Genetics, Oncology +14

Radial glia cells are candidate stem cells of ependymoma

Michael D. Taylor, Helen Poppleton, Christine Fuller et al. · Cancer Cell · 2005 · 824 citations · Full text

Medicine, Cell Biology, Oncology +14

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

Tanya Basu, David H. Gutmann, Jonathan A. Fletcher et al. · Nature · 1992 · 669 citations · Full text

Medicine, Cancer Biology, Oncology +17

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.

Camilynn I. Brannan, Archibald S. Perkins, Kristine S. Vogel et al. · Genes & Development · 1994 · 644 citations · Full text

Life Sciences, Developmental Biology, Genetics +14