Critical Care Medicine · 1998 · 242 citations · 30 references
In patients with severe acute brain trauma and intracranial hypertension associated with compromised cerebrospinal fluid spaces, monitoring and managing cerebral extraction of oxygen in conjunction with cerebral perfusion pressure result in better outcome than when cerebral perfusion pressure is managed alone.
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Cerebral blood flow and metabolism in comatose patients with acute head injury
Walter D. Obrist, Thomas W. Langfitt, Jurg L. Jaggi et al. · Journal of neurosurgery · 1984 · 841 citations