Analysis of the genes encoding immunodominant piroplasm surface proteins of Theileria sergenti and Theileria buffeli by nucleotide sequencing and polymerase chain reaction

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.2K citations

Life Sciences, Biotechnology, Molecular Biology +12

A new method for predicting signal sequence cleavage sites

Gunnar von Heijne · Nucleic Acids Research · 1986 · 4.6K citations · Full text

Life Sciences, Bioinformatics, Biology +11

Dideoxy sequencing method using denatured plasmid templates

Masahira Hattori, Yoshiyuki Sakaki · Analytical Biochemistry · 1986 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +8

Primary structure of the 175K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion.

B. Kim Lee Sim, Palmer A. Orlandi, J. David Haynes et al. · The Journal of Cell Biology · 1990 · 219 citations · Full text

Life Sciences, Immunology, Molecular Biology +17