Functional mutation analysis of EGFR family genes and corresponding lymph node metastases in head and neck squamous cell carcinoma

Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella et al. · New England Journal of Medicine · 2004 · 11.5K citations

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Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck

James A. Bonner, Paul M. Harari, J. Giralt et al. · New England Journal of Medicine · 2006 · 5.1K citations · Full text

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Multicenter Phase II Study of Erlotinib, an Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

Denis Soulières, Neil Senzer, Everett E. Vokes et al. · Journal of Clinical Oncology · 2003 · 808 citations · Full text

Medicine, Oncology, Pharmacology +11

Phase II Trial of ZD1839 in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Ezra E.W. Cohen, Fred Rosen, Walter M. Stadler et al. · Journal of Clinical Oncology · 2003 · 607 citations

Medicine, Oncology, Pharmacotherapy +13

An Alternative Inhibitor Overcomes Resistance Caused by a Mutation of the Epidermal Growth Factor Receptor

Susumu Kobayashi, Hongbin Ji, Yuki Yuza et al. · Cancer Research · 2005 · 271 citations · Full text

Medicine, Oncology, Pharmacology +16