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Effect of anti-stress plants on biochemical changes during stress reaction
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1991
Year
Environmental StressBotanySiberian PlantAbiotic DamageSocial SciencesOxidative StressBiosynthesisPlant StressAbiotic StressBiotic StressStressOcimum SanctumNeurochemistryStress HormoneBiochemistryBehavioural PharmacologyNeuropharmacologyIndian PlantNervous SystemDopaminePharmacologyChemical StressorPhysiologyStress PhysiologyStress ReactionNeuroscienceBiological PsychiatryMedicinePlant Physiology
1. Effect of alcoholic extracts of plants, Eleutherococcus senticosus (Siberian plant) and Ocimum sanctum (Indian plant) described earlier as anti-stress agents was studied on the changes in central neurotransmitter (adrenaline, noradrenaline, dopamine, 5-hydroxytrypamine) levels and enzyme (monoamine oxidase) activity in the brain induced by stressors. 2. Two kinds of stressors were used, 5 hours swimming in mice and 2 hours gravitational stress in rats. 3. There was an increase in the levels of dopamine (DA) and 5-hydroxytryptamine (5-HT) and decrease in adrenaline (A) noradreneline (NA) and monoamine oxidase (MOA) in stressed animals. 4. Both anti-stress drugs prevented the decrease in A, NA, MAO and 5-HT. The increase in DA was facilitated. 5. Prevention and facilitation of changes in brain neurotransmitters and enzymes by anti-stress agents appear to enhance the stress-adaptation phenomenon for better coping of the organism during stressful situations.