Neurosurgery · 2012 · 51 citations · 20 references
In this case, a region with low WSS at end diastole and high pressure at peak systole was at the rupture site. A possible mechanism of rupture in this particular aneurysm is that low WSS at end diastole caused degeneration and thinning of the aneurysm wall and that high pressure at peak systole (impingement zone) resulted in rupture of the thinning wall.
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Hemodynamic Shear Stress and Its Role in Atherosclerosis
Adel M. Malek · JAMA · 1999 · 3.5K citations
David N. Ku, Don P. Giddens, Christopher K. Zarins et al. · Arteriosclerosis An Official Journal of the American Heart Association Inc · 1985 · 2.7K citations · Full text
Magnitude and Role of Wall Shear Stress on Cerebral Aneurysm
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Hemodynamic–Morphologic Discriminants for Intracranial Aneurysm Rupture
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Juan R. Cebral, Marcelo A. Castro, Sunil Appanaboyina et al. · IEEE Transactions on Medical Imaging · 2005 · 530 citations
Engineering, Cerebral Aneurysm Hemodynamics, Blood Flow Patterns +24