Essential structural factors of annonaceous acetogenins as potent inhibitors of mitochondrial complex I

Cell biological mechanisms of multidrug resistance in tumors.

Sanford M. Simon, Melvin Schindler · Proceedings of the National Academy of Sciences · 1994 · 371 citations

Tumor Biology, Drug Targeting, Chemoprevention Strategy +14

Two binding sites of inhibitors in NADH:ubiquinone oxidoreductase (complex I)

Thorsten Friedrich, Petra van Heek, Hans Leif et al. · European Journal of Biochemistry · 1994 · 250 citations · Full text

Inhibitory Activity, Biochemistry, Natural Sciences +11

Natural substances (acetogenins) from the family <i>Annonaceae</i> are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I)

Mauro Degli Esposti, Anna Ghelli, Marina Ratta et al. · Biochemical Journal · 1994 · 238 citations · Full text

Phytoalexin, Complex I. Rolliniastatin-1, Mitochondrial Function +14

Annonaceous acetogenins: An updated review

Xin-ping Fang, Matthew J. Rieser, Zhe-ming Gu et al. · Phytochemical Analysis · 1993 · 195 citations

Bioorganic Chemistry, Biochemistry, Annonaceous Acetogenins +9

Structure−Activity Relationships of Diverse Annonaceous Acetogenins against Multidrug Resistant Human Mammary Adenocarcinoma (MCF-7/Adr) Cells

Nicholas H. Oberlies, Ching‐Jer Chang, Jerry L. McLaughlin · Journal of Medicinal Chemistry · 1997 · 178 citations