Is a Cortical Spike Discharge “Transferred” to the Contralateral Cortex via the Corpus Callosum?: An Intraoperative Observation of Electrocorticogram and Callosal Compound Action Potentials

Abstract

If the "transfer" role of the CC is true, interhemispheric delays between BSSWs must be longer than interhemispheric axonal conduction time (about 20 ms), and a preceding cortical spike discharge must produce a CCAP and then a contralateral one in order of time. However, this hypothesis was not confirmed in the present study. We propose the interhemispheric recruitment of the epileptogenic state as a different role of the CC on epileptogenesis.