Sensitive detection of microRNA by chronocoulometry and rolling circle amplification on a gold electrode

Bo Yao, Yichen Liu, Miyuki Tabata, Huangtianzhi Zhu, Yuji Miyahara

Chemical Communications · 2014 · 75 citations · 26 references

Concepts

Abstract

We developed a quantitative detection scheme for nucleic acids, combining solid-phase rolling circle amplification and chronocoulometry (RCA-CC). A gold electrode was directly formed on a polystyrene substrate as a cost-effective and flexible biosensor for sensitive detection of microRNA (mir-143) in blood samples.

References

26