Sensors · 2012 · 30 citations · 23 references
EngineeringBioengineeringElectrical EngineeringBiosensorsSemiconductor DevicesSensorsBiomedical SensorsBiosensor DesignDna BiosensorsMicroscale BiosensorsNanosensorsNanowiresNano SensorsNanobiosensorsNanowire BiosensorsNanowire DevicesNanowire SensorsNon-volatile MemoryPh SensitivitySensor Technology
This paper reports a versatile nano-sensor technology using "top-down" poly-silicon nanowire field-effect transistors (FETs) in the conventional Complementary Metal-Oxide Semiconductor (CMOS)-compatible semiconductor process. The nanowire manufacturing technique reduced nanowire width scaling to 50 nm without use of extra lithography equipment, and exhibited superior device uniformity. These n type polysilicon nanowire FETs have positive pH sensitivity (100 mV/pH) and sensitive deoxyribonucleic acid (DNA) detection ability (100 pM) at normal system operation voltages. Specially designed oxide-nitride-oxide buried oxide nanowire realizes an electrically V(th)-adjustable sensor to compensate device variation. These nanowire FETs also enable non-volatile memory application for a large and steady V(th) adjustment window (>2 V Programming/Erasing window). The CMOS-compatible manufacturing technique of polysilicon nanowire FETs offers a possible solution for commercial System-on-Chip biosensor application, which enables portable physiology monitoring and in situ recording.
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Nanowire Nanosensors for Highly Sensitive and Selective Detection of Biological and Chemical Species
Yi Cui, Qingqiao Wei, Hongkun Park et al. · Science · 2001 · 5.8K citations
P. Bergveld · Sensors and Actuators B Chemical · 2002 · 1.6K citations · Full text
Label-free immunodetection with CMOS-compatible semiconducting nanowires
Eric Stern, James F. Klemic, David A. Routenberg et al. · Nature · 2007 · 1.3K citations