Letters in Organic Chemistry · 2005 · 13 citations · 0 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsIsoxazole ChemistryIsoxazole SynthesisRing-forming Reactions
A series of substituted 3-bromoisoxazoles were ring opened with either molybdenum hexacarbonyl or iron (II)chloride tetrahydrate to give β -ketonitriles in good yields. Keywords: isoxazole, ketonitrile, molybdenum hexacarbonyl, ferrous chloride, reductive ring opening