Archives of General Psychiatry · 1990 · 191 citations · 18 references
Social SciencesPsychiatryPsychologyDevelopmental PsychologyDevelopmental PsychopathologySubstance Use DisordersAlcohol DependenceAlcohol Use DisorderPersonality DisordersAntisocial Personality Traits
Alcoholics have been proposed to be comprised of subtypes who differ in their age at onset and in type 1 vs type 2 characteristics. This study examined whether the clinical course of primary alcoholics was associated with age at onset as well as the type 1-vs-type 2 classification scheme. Interviews with 171 consecutive primary alcoholic men entering an alcohol treatment program revealed that age at onset of alcoholism was correlated with alcohol, drug, and childhood criminality problem histories. Neither classification of these alcoholics into discrete type 1 and type 2 categories nor placing them along a continuum of type 2 characteristics was consistently associated with severity of clinical histories. These findings underscore the clinical importance of age at onset and suggest the possibility that the type 2 prototype might represent a separate diagnosis, antisocial personality disorder, and not alcoholism itself.
18
Neurogenetic Adaptive Mechanisms in Alcoholism
C. Robert Cloninger · Science · 1987 · 2.3K citations
The Disease Concept of Alcoholism.
Howard J. Ehrlich, E. M. Jellinek · American Sociological Review · 1961 · 1.1K citations
Alcoholism and Antisocial Personality
Remi J. Cadoret, Thomas W. O’Gorman, Ed Troughton et al. · Archives of General Psychiatry · 1985 · 335 citations
Platelet MAO activity as a biological marker in subgroups of alcoholism
A.‐L. von Knorring, M Bohman, Lars von Knorring et al. · Acta Psychiatrica Scandinavica · 1985 · 312 citations