European Journal of Organic Chemistry · 2007 · 15 citations · 34 references
Ring ClosureEnantioselective SynthesisEngineeringNatural SciencesDiversity-oriented SynthesisOrganic ChemistryNatural ProductsChemistryHeterocycle ChemistryAsymmetric CatalysisEnantiopure 1‐AzaspiroBiomolecular EngineeringGood Yields
Abstract The 5‐ endo iodine‐promoted ring closure of 4‐allyl‐4‐(alkylamino)cyclohexanone derivatives gives the corresponding 1‐azaspiro[4.5]decanes in good yields. The reaction was tested with enantiopure homoallylamines to evaluate the diastereoselectivity of the process and to provide a route for possible intermediates to the natural products embodying this azabicyclic ring.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
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Synthetic Use of Molecular Iodine for Organic Synthesis
Hideo Togo, Shinpei Iida · Synlett · 2006 · 409 citations
Further Improvements of the Synthesis of Alkynes from Aldehydes
Gerald J. Roth, Bernd Liepold, S. Müller et al. · Synthesis · 2003 · 206 citations