The EGF-CFC Protein One-Eyed Pinhead Is Essential for Nodal Signaling

Kira Gritsman, Jiaojiao Zhang, Simon K. Cheng, +3

Cell

Cripto is required for correct orientation of the anterior–posterior axis in the mouse embryo

Jixiang Ding, Lu Yang, Yu‐Ting Yan, +4

Nature

BiologyDevelopmental BiologyDevelopmental GeneticsAnterior–posterior AxisMorphogenesis +7

Gene expression in human embryonic stem cell lines: unique molecular signature

Bhaskar Bhattacharya, Takumi Miura, Ralph Brandenberger, +12

Blood

Nodal Signals to Smads through Cripto-Dependent and Cripto-Independent Mechanisms

Chang‐Yeol Yeo, Malcolm Whitman

Molecular Cell

Signal TransductionMolecular PhysiologyNodal SignalsSignaling PathwaySignal Recognition +4

Differential expression of epidermal growth factor-related proteins in human colorectal tumors.

Fortunato Ciardiello, N Kim, Toshiaki Saeki, +7

Proceedings of the National Academy of Sciences

PathologyGrowth Factor AlphaCancer BiologyTumor BiologySignaling Pathway +15

Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo

Heather B. Adkins, Caterina Bianco, Susan G. Schiffer, +15

Journal of Clinical Investigation

Cripto-1 Activates Nodal- and ALK4-Dependent and -Independent Signaling Pathways in Mammary Epithelial Cells

Caterina Bianco, Heather B. Adkins, Christian Wechselberger, +10

Molecular and Cellular Biology

Expression of cripto, a novel gene of the epidermal growth factor gene family, leads to in vitro transformation of a normal mouse mammary epithelial cell line.

Fortunato Ciardiello, Rosanna Dono, N. Kim, +2

PubMed

Transforming GeneNovel GenePathologyCell ProliferationCell Growth +17

A Nodal- and ALK4-independent signaling pathway activated by Cripto-1 through Glypican-1 and c-Src.

Caterina Bianco, Luigi Strizzi, Aasia Rehman, +10

PubMed

Molecular RegulationMolecular BiologyCytoskeletonSignaling PathwayCell Regulation +16

A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects

June M. de la Cruz, Richard N. Bamford, Rebecca D. Burdine, +5

Human Genetics

Cfc DomainDevelopmental BiologyLoss-of-function MutationSomatic VariantGenetic Disorder +5