A point mutation in the mitochondrial tRNALeu(UUR) gene in melas (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes)

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

Randall K. Saiki, David H. Gelfand, Susanne Stoffel et al. · Science · 1988 · 17.2K citations

Life Sciences, Biotechnology, Molecular Biology +12

Sequence and organization of the human mitochondrial genome

Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature · 1981 · 9.7K citations

Medicine, Genetics, Molecular Genetics +12

Mitochondrial DNA Mutation Associated with Leber's Hereditary Optic Neuropathy

Douglas C. Wallace, Gurparkash Singh, Marie T. Lott et al. · Science · 1988 · 2.4K citations

Life Sciences, Genetics, Molecular Genetics +17

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

Ian Holt, A. E. Harding, J A Morgan-Hughes · Nature · 1988 · 1.8K citations

Life Sciences, Genetics, Molecular Genetics +14

Sequence and gene organization of mouse mitochondrial DNA

Maureen J. Bibb, Richard A. Van Etten, C T Wright et al. · Cell · 1981 · 1.7K citations

Medicine, Genetics, Molecular Genetics +14