Concepedia

Epicutaneous exposure to nickel induces nickel allergy in mice via a <scp>MyD88</scp>‐dependent and interleukin‐1‐dependent pathway

Marie T. Vennegaard, Beatrice Dyring‐Andersen, Lone Skov, Morten M. Nielsen, Jonas Damgård Schmidt, Michael Bzorek, Steen Seier Poulsen, Allan Randrup Thomsen, Anders Woetmann, Jacob P. Thyssen,

Contact Dermatitis · 2014 · 31 citations · 43 references

DOI

Abstract

This new model for nickel allergy that reflects epicutaneous exposure to nickel in humans shows that nickel allergy is dependent on MyD88 and IL-1 receptor signalling, but independent of TLR4.

References

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