Caffeic acid phenethyl ester promotes anti-inflammatory effects by inhibiting MAPK and NF-κB signaling in activated HMC-1 human mast cells

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

Zhou Zhu, Robert Homer, Zhonde Wang et al. · Journal of Clinical Investigation · 1999 · 1.7K citations · Full text

Asthma, Inflammatory Lung Disease, Lung Inflammation +21

Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.

Kasthuri Natarajan, Sandeep Singh, Terrence R. Burke et al. · Proceedings of the National Academy of Sciences · 1996 · 1.1K citations · Full text

Specific Inhibitor, Chemoprevention Strategy, Immunology +18

Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.

Pedro Michaluart, Jaime L. Masferrer, Adelaide M. Carothers et al. · PubMed · 1999 · 375 citations

Pge2 Synthesis, Chemoprevention Strategy, Lipid Peroxidation +17

Caffeic acid is a selective inhibitor for leukotriene biosynthesis

Yasuko Koshihara, Tomohiro Neichi, Sei‐itsu Murota et al. · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1984 · 347 citations

Biosynthesis, Biochemistry, Phytochemical +3

Inhibitors of human immunodeficiency virus integrase.

Mark R. Fesen, Kurt W. Kohn, François Leteurtre et al. · Proceedings of the National Academy of Sciences · 1993 · 278 citations · Full text

Immunology, Pharmacotherapy, Antiviral Drug +16