Synthetic Communications · 2007 · 17 citations · 26 references
Natural SciencesChemistryOrganic ChemistryHeterocyclic ChemistryCyanohydrin FormationKetonesMild Reaction Conditions
Abstract A combination of tetrachlorosilane and potassium cyanide (in situ trichlorosilyl cyanide) was found to work efficiently for hydrocyanation of ketones to afford the corresponding cyanohydrins in high yield under mild conditions.
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