Concepedia

Decreased serum antioxidant capacity in patients with Wilson disease is associated with neurological symptoms

Radan Brůha, Z Mareček, Lenka Pospíšilová, Soňa Nevšímalová, Pavel Martásek, J Petrtýl, Petr Urbánek, Alena Jirásková, Ivana Malíková, Martin Haluzı́k,

Journal of Inherited Metabolic Disease · 2011 · 33 citations · 35 references

DOI

Abstract

Data from our study suggest that the increased oxidative stress contributes significantly to the clinical manifestation of WD; as a lower TAC is associated with the neurological symptoms in WD patients.

References

35

The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene

Peter C. Bull, Gordon R. Thomas, Johanna M. Rommens et al. · Nature Genetics · 1993 · 1.9K citations

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The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

Rudolph E. Tanzi, Konstantin Petrukhin, Jean‐Luc Pellequer et al. · Nature Genetics · 1993 · 1.4K citations

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Diagnosis and treatment of Wilson disease: An update

Eve A. Roberts, Michael L. Schilsky · Hepatology · 2008 · 1.3K citations · Full text

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Clinical presentation, diagnosis and long-term outcome of Wilson’s disease: a cohort study

Uta Merle, Mark Schaefer, Péter Ferenci et al. · Gut · 2006 · 612 citations · Full text

The Wilson disease gene: spectrum of mutations and their consequences

Gordon R. Thomas, John Forbes, Eve A. Roberts et al. · Nature Genetics · 1995 · 571 citations

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