Psychosomatic Medicine · 1976 · 562 citations · 0 references
Sleep DisordersPain MedicineNeuropathic PainFibromyalgiaMuscle TendernessOrthopaedic SurgeryPain SyndromeMusculoskeletal DisordersChronic Musculoskeletal ConditionSleep Stage DeprivationPain ManagementHealth SciencesRheumatologySleepRehabilitationMusculoskeletal PainSleep DeprivationPain ResearchSleep DisorderRem SleepMedicineNeuromusculoskeletal Disorder
These results are discussed in the light of the previously postulated relationship between NREM sleep disturbance and musculoskeletal pain in patients with so‑called “Fibrositis syndrome.” Two groups of young, healthy, nonathletic volunteers were subjected to selective sleep stage deprivation: six subjects were deprived of stage 4 sleep and seven of REM sleep. Stage 4 deprivation produced more musculoskeletal symptoms and increased muscle tenderness compared to REM deprivation, which showed no such changes.
Two groups of young, healthy, nonathletic volunteers were subjected to selective sleep stage deprivation. Six subjects were deprived of stage 4 sleep and seven subjects of REM sleep. The stage 4 deprived group reported more musculoskeletal symptoms during the deprivation condition than did the REM deprived group. The stage 4 deprived group also showed a significant increase in muscle tenderness between the baseline and deprivation conditions and an altered pattern of overnight change in muscle tenderness in response to deprivation. The REM deprived group did not show either of these changes. These results are discussed in the light of the previously postulated relationship between NREM sleep disturbance and muscoloskeletal pain in patients with so-called "Fibrositis syndrome."