HIV protease inhibitors block adipogenesis and increase lipolysis in vitro

Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

Frank J. Palella, Kathleen M. Delaney, Anne C. Moorman et al. · New England Journal of Medicine · 1998 · 9.5K citations

Public Health, Infectious Disease Control, Infectious Diseases +15

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors

Andrew Carr, Katherine Samaras, Samantha Burton et al. · AIDS · 1998 · 2.4K citations

Medicine, Endocrinology, Nutrition +17

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

Peter Tontonoz, E Hu, Reed A. Graves et al. · Genes & Development · 1994 · 2.2K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.

Kristina Schoonjans, Julia Peinado‐Onsurbe, Anne‐Marie Lefebvre et al. · The EMBO Journal · 1996 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16