Liquid chromatography–mass spectrometry/mass spectrometry method development for drug metabolism studies: Examining lipid matrix ionization effects in plasma

Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC−MS/MS

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Practical HPLC Method Development

Analytical Chemistry · 1993 · 1.4K citations

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The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds

Ryan P. Bonfiglio, Richard C. King, Timothy Olah et al. · Rapid Communications in Mass Spectrometry · 1999 · 922 citations

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +10

Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids:  A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

B.K. Matuszewski, M.L. Constanzer, C.M. Chavez-Eng · Analytical Chemistry · 1998 · 879 citations

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Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography–tandem mass spectrometry

Cara Polson, Pratibha Sarkar, Bev Incledon et al. · Journal of Chromatography B · 2003 · 678 citations

Life Sciences, Biochemistry, Molecular Biology +16