Retrospective Diagnosis by Serologic Means of Congenitally Acquired Rubella Infections

Abstract

THE teratogenic potential of rubella virus has been the subject of continuing assessment since Gregg1 established a causal relation between maternal rubella and the occurrence of congenital cataracts and congenital heart disease. Shortly thereafter deafness was reported as a feature of the syndrome of congenital rubella, and more refined studies have recently indicated that lesser degrees of impairment of hearing in children are a common consequence of rubella during the first sixteen weeks of pregnancy.2 Rubella has also been incriminated as an etiologic factor in abortions and stillbirths, in prematurity and in physical and mental retardation, as well as in . . .