Clinical Consequences of IL-1 Genotype on Early Implant Failures in Patients under Periodontal Maintenance

Abstract

The overall implant failure rate in a population treated and maintained for periodontal disease is similar to that of healthy subjects. A synergistic effect found between smoking and a positive IL-1 genotype resulted in a significantly higher implant loss. This indicates that further research with a larger patient group should focus on multifactorial analysis for adequate risk assessment.