Isoallopregnanolone; an antagonist to the anaesthetic effect of allopregnanolone in male rats

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

Maria Dorota Majewska, Neil L. Harrison, Rochelle D. Schwartz et al. · Science · 1986 · 2.2K citations

Medicine, Neuroscience, Pharmacology +17

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain.

R. H. Purdy, A. Leslie Morrow, Perry H. Moore et al. · Proceedings of the National Academy of Sciences · 1991 · 960 citations

Life Sciences, Neurobiology, Neuroscience +14

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

Daniel Bitran, Robert J. Hilvers, Carol K. Kellogg · Brain Research · 1991 · 457 citations · Full text

Medicine, Neuroscience, Pharmacology +12

EPILEPTIC SEIZURES IN WOMEN RELATED to PLASMA ESTROGEN and PROGESTERONE DURING the MENSTRUAL CYCLE

Torbjörn Bäckström · Acta Neurologica Scandinavica · 1976 · 389 citations

Medicine, Endocrinology, Neuroscience +14

Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation.

Tushar G. Kokate, Björn E. Svensson, Michael A. Rogawski · Journal of Pharmacology and Experimental Therapeutics · 1994 · 354 citations

Medicine, Neuroscience, Pharmacology +13