Gender Differences: Their Ontogeny and Significance

U. Mittwoch

Journal of Medical Genetics · 1973 · 89 citations · 0 references

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Abstract

Reviewsplasia, in which both resting cartilage and echondral ossification are relatively normal, are distinguished from those in thanatophoric dwarfism and metaphyseal dysos- tosis, in which resting cartilage is normal and enchondral ossification is disrupted, and from those in achondro- genesis and metatropic dwarfism type II, in which resting cartilage is abnormal and the defect in enchondral ossi- fication is apparently secondary to the defect in epiphyseal cartilage.In the chapters on specific disorders the main em- phasis is on the radiological appearances, including the changes with age and the radiological differential diag- nosis.The radiographs are of excellent quality.The clinical features, including course and prognosis, are also described briefly.The genetics of each condition are also didactically given.Full references are listed for the radiological appearance and one or two key references for the clinical aspects.C. 0.