Concepedia

Reduced cerebrovascular reactivity in young adults carrying the <i>APOE</i> ε4 allele

Sana Suri, Clare E. Mackay, Michael Kelly, Michael Germuska, Elizabeth M. Tunbridge, Giovanni B. Frisoni, Paul M. Matthews, Klaus P. Ebmeier, Daniel P. Bulte, Nicola Filippini

Alzheimer s & Dementia · 2014 · 111 citations · 35 references

DOI

Abstract

Because CO2-CVR gauges vascular health, the differential effect of APOE in young adults may reflect a vascular contribution to the vulnerability of ε4-carriers to late-life pathology. Studies confirming our findings are warranted.

References

35

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Douglas N. Greve, Bruce Fischl · NeuroImage · 2009 · 3.9K citations · Full text

, , +5

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, , +6

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Brian Patenaude, Stephen M. Smith, David N. Kennedy et al. · NeuroImage · 2011 · 2.3K citations · Full text

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