Atypicality of Several Antipsychotics on the Basis of In Vivo Dopamine-D2 and Serotonin-5HT2 Receptor Occupancy

Clozapine for the Treatment-Resistant Schizophrenic

John M. Kane · Archives of General Psychiatry · 1988 · 4.1K citations

Medicine, Pharmacology, Psychiatry +16

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

Ian Creese, David R. Burt, Solomon H. Snyder · Science · 1976 · 2.2K citations

Medicine, Neuroscience, Pharmacology +14

Antipsychotic drug doses and neuroleptic/dopamine receptors

Philip Seeman, T. Lee, M. Chau-Wong et al. · Nature · 1976 · 1.6K citations

Medicine, Pharmacology, Psychiatry +13

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

Herbert Y. Meltzer, Shin Matsubara, J C Lee · Journal of Pharmacology and Experimental Therapeutics · 1989 · 1.4K citations

Medicine, Pharmacology, Psychiatry +17

Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors

J E Leysen, Paul M. F. Janssen, Alain Schotte et al. · Psychopharmacology · 1993 · 336 citations

Medicine, Neuroscience, Pharmacology +16