Concepedia

Overexpression of fatty acid synthase in human gliomas correlates with the WHO tumor grade and inhibition with Orlistat reduces cell viability and triggers apoptosis

Susanne Grube, Pedro Dünisch, Diana Freitag, Maren Klausnitzer, Yasser Sakr, Jan Walter, Rolf Kalff, Christian Ewald

Journal of Neuro-Oncology · 2014 · 89 citations · 37 references

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References

37

A new mathematical model for relative quantification in real-time RT-PCR

Michael W. Pfaffl · Nucleic Acids Research · 2001 · 34.3K citations · Full text

Reduced Food Intake and Body Weight in Mice Treated with Fatty Acid Synthase Inhibitors

Thomas M. Loftus, Donna E. Jaworsky, Gojeb L. Frehywot et al. · Science · 2000 · 1K citations

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

Jae Bum Kim, Pasha Sarraf, Margaret E. Wright et al. · Journal of Clinical Investigation · 1998 · 776 citations · Full text

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Orlistat Is a Novel Inhibitor of Fatty Acid Synthase with Antitumor Activity

Steven J. Kridel, Fumiko Axelrod, Natasha Rozenkrantz et al. · Cancer Research · 2004 · 589 citations · Full text

Synthesis and antitumor activity of an inhibitor of fatty acid synthase

Francis P. Kuhajda, Ellen S. Pizer, Ji Nong Li et al. · Proceedings of the National Academy of Sciences · 2000 · 562 citations