Concepedia

Sequential combination thrombolytic therapy for acute myocardial infarction: results of the pro-urokinase and t-PA enhancement of thrombolysis (PATENT) trial

Stuart Zarich, Glen J. Kowalchuk, W. Douglas Weaver, Joseph Loscalzo, Michael A. Sassower, Karen Manzo, Christine M. Byrnes, James E. Muller, Victor Gurewich

Journal of the American College of Cardiology · 1995 · 62 citations · 37 references

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Abstract

A sequential combination of low dose rt-PA and reduced-dose pro-urokinase produced a high TIMI 3 patency rate, was well tolerated and was associated with a low reocclusion rate.

References

37

An International Randomized Trial Comparing Four Thrombolytic Strategies for Acute Myocardial Infarction

New England Journal of Medicine · 1993 · 4K citations · Full text

The Effects of Tissue Plasminogen Activator, Streptokinase, or Both on Coronary-Artery Patency, Ventricular Function, and Survival after Acute Myocardial Infarction

The GUSTO Angiographic Investigators · New England Journal of Medicine · 1993 · 1.9K citations · Full text

A Randomized Trial of Immediate versus Delayed Elective Angioplasty after Intravenous Tissue Plasminogen Activator in Acute Myocardial Infarction

Eric J. Topol, Robert M. Califf, Barry S. George et al. · New England Journal of Medicine · 1987 · 945 citations

ISIS-3: a randomised comparison of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41 299 cases of suspected acute myocardial infarction

The Lancet · 1992 · 920 citations

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ISIS-3 - A RANDOMIZED COMPARISON OF STREPTOKINASE VS TISSUE PLASMINOGEN-ACTIVATOR VS ANISTREPLASE AND OF ASPIRIN PLUS HEPARIN VS ASPIRIN ALONE AMONG 41,299 CASES OF SUSPECTED ACUTE MYOCARDIAL-INFARCTION

D Hunt, George Varigos, F Dienstl et al. · Oxford University Research Archive (ORA) (University of Oxford) · 1992 · 898 citations

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