Synthesis of VS-105: A novel and potent vitamin D receptor agonist with reduced hypercalcemic effects

Distinct Conformational Changes Induced by 20-epi Analogues of 1α,25-Dihydroxyvitamin D3 Are Associated with Enhanced Activation of the Vitamin D Receptor

Sara Peleg, M. S. Sastry, Elaine D. Collins et al. · Journal of Biological Chemistry · 1995 · 203 citations · Full text

Medicine, Biochemistry, Pharmacology +15

Selective Interaction of Vitamin D Receptor with Transcriptional Coactivators by a Vitamin D Analog

Ken‐ichi Takeyama, Yoshikazu Masuhiro, Hiroaki Fuse et al. · Molecular and Cellular Biology · 1999 · 200 citations

Medicine, Molecular Biology, Pharmacology +17

A potent analog of 1α,25-dihydroxyvitamin D ₃ selectively induces bone formation

Nirupama K. Shevde, Lori A. Plum, Margaret Clagett‐Dame et al. · Proceedings of the National Academy of Sciences · 2002 · 175 citations · Full text

Medicine, Endocrinology, Pharmacology +17

New 1α,25-Dihydroxy-19-norvitamin D₃ Compounds of High Biological Activity:  Synthesis and Biological Evaluation of 2-Hydroxymethyl, 2-Methyl, and 2-Methylene Analogues

Rafał R. Siciński, Jean M. Prahl, Connie M. Smith et al. · Journal of Medicinal Chemistry · 1998 · 157 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Vitamin D derivatives acutely reduce endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat

Michael S. K. Wong, Rémi Delansorne, Ricky Y.K. Man et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2008 · 127 citations

Medicine, Pharmacology, Physiology +16