Sedum alkaloids. V. Sedacrine, the major alkaloid of <i>Sedum</i><i>acre</i>, and related bases

Abstract

Sedacrine, the major alkaloid of Sedumacre, is assigned structure 5 on the basis of spectroscopic and chemical evidence. Two minor bases, sedinone 6 and dihydrosedinine 7, are described. Sedacrine 5, sedinone 6, dihydrosedinine 7, and sedinine 3 are correlated. The absolute configurations of these alkaloids and that of sedacryptine 2 are established.