Enhancement of functional antibody responses to AMA1-C1/Alhydrogel®, a Plasmodium falciparum malaria vaccine, with CpG oligodeoxynucleotide

CpG motifs in bacterial DNA trigger direct B-cell activation

Arthur Μ. Krieg, Ae‐Kyung Yi, Sara Matson et al. · Nature · 1995 · 3.5K citations

Life Sciences, Microbiology, Molecular Biology +10

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.

Dennis M. Klinman, Ae‐Kyung Yi, Serge L. Beaucage et al. · Proceedings of the National Academy of Sciences · 1996 · 1.5K citations

Life Sciences, Immunology, Microbiology +17

CpG DNA Is a Potent Enhancer of Specific Immunity in Mice Immunized with Recombinant Hepatitis B Surface Antigen

Heather L. Davis, Risini Weeranta, Thomas J. Waldschmidt et al. · The Journal of Immunology · 1998 · 681 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice

Cynthia L. Brazolot Millan, Risini D. Weeratna, Arthur Μ. Krieg et al. · Proceedings of the National Academy of Sciences · 1998 · 345 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

CPG 7909, an Immunostimulatory TLR9 Agonist Oligodeoxynucleotide, as Adjuvant to Engerix-B� HBV Vaccine in Healthy Adults: A Double-Blind Phase I/II Study

Curtis Cooper, Heather L. Davis, Mary L. Morris et al. · Journal of Clinical Immunology · 2004 · 330 citations

Life Sciences, Immunology, Infectious Diseases +17