Piperacillin/Tazobactam Therapy for Diabetic Foot Infection

Anneke M. Zeillemaker, Karin‐Ellen Veldkamp, Marian G.J. van Kraaij, J. B. L. Hoekstra, Arthur A.G.M. Hoynck van Papendrecht, R.J.A. Diepersloot

Foot & Ankle International · 1998 · 32 citations · 7 references

Concepts

Abstract

In this study, 29 patients were hospitalized with a diabetic foot infection and were treated with piperacillin/tazobactam. Of these 23 patients who were evaluated for efficacy of treatment, 22 patients improved or were clinically cured. In seven patients (30%), there was persistence of one of the baseline pathogens. Adverse events were reported in 15 patients (58%), three of which were serious. Piperacillin/tazobactam may be useful as monotherapy in diabetic foot infection giving an adequate clinical response and the level of side effects equivalent to those of other broad-spectrum antibiotics.

References

7