Evaluation of DNA damage by alkaline elution technique after inhalation exposure of rats and mice to 1,3-butadiene

Evaluation of the alkaline elution/rat hepatocyte assay as a predictor of carcinogenic/mutagenic potential

Joseph F. Sina, Christian L. Bean, Gary Dysart et al. · Mutation Research/Environmental Mutagenesis and Related Subjects · 1983 · 331 citations

Pharmacy, Toxicology, Biochemical Toxicology +13

Hepatic microsomal metabolism of 1,3-butadiene

Etienne Malvoisin, Marcel Roberfroid · Xenobiotica · 1982 · 139 citations

Life Sciences, Biochemistry, Metabolism +9

Species differences in the disposition of inhaled butadiene

James A. Bond, Alan R. Dahl, Rogene F. Henderson et al. · Toxicology and Applied Pharmacology · 1986 · 91 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Biological activation of 1,3-butadiene to vinyl oxirane by rat liver microsomes and expiration of the reactive metabolite by exposed rats

Hermann M. Bolt, G. Schmiedel, J. G. Filser et al. · Journal of Cancer Research and Clinical Oncology · 1983 · 83 citations · Full text

Pharmacy, Biochemistry, Toxicology +14

Identification and quantitation of 1,2-epoxybutene-3 as the primary metabolite of 1,3-butadiene

Etienne Malvoisin, G. Lhoëst, F. Poncelet et al. · Journal of Chromatography A · 1979 · 82 citations

Life Sciences, Chemistry, Toxicology +7