Concepedia

A monoclonal antibody against the platelet glycoprotein IIb/IIIa receptor complex prevents platelet aggregation and thrombosis in a canine model of coronary angioplasty.

Eric Bates, Mark J. McGillem, Judith K. Mickelson, Bertram Pitt, G.B. John Mancini

Circulation · 1991 · 76 citations · 32 references

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Abstract

In this animal model, the 7E3 antiplatelet antibody is superior to aspirin in inhibiting platelet aggregation, thrombosis, and acute closure after deep arterial injury caused by coronary balloon angioplasty.

References

32

A Randomized Trial of Immediate versus Delayed Elective Angioplasty after Intravenous Tissue Plasminogen Activator in Acute Myocardial Infarction

Eric J. Topol, Robert M. Califf, Barry S. George et al. · New England Journal of Medicine · 1987 · 945 citations

Aspirin and Dipyridamole in the Prevention of Re-Stenosis after Percutaneous Transluminal Coronary Angioplasty

Leonard Schwartz, Martial G. Bourassa, Jacques Lespérance et al. · New England Journal of Medicine · 1988 · 694 citations

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THROMBOLYSIS WITH TISSUE PLASMINOGEN ACTIVATOR IN ACUTE MYOCARDIAL INFARCTION: NO ADDITIONAL BENEFIT FROM IMMEDIATE PERCUTANEOUS CORONARY ANGIOPLASTY

M. L. Simoons · The Lancet · 1988 · 660 citations

, , +9

Balloon angioplasty. Natural history of the pathophysiological response to injury in a pig model.

Peter M. Steele, James H. Chesebro, Anthony W. Stanson et al. · Circulation Research · 1985 · 632 citations

, , +23

A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.

Barry S. Coller · Journal of Clinical Investigation · 1985 · 589 citations · Full text

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