DETECTION OF CIRCULATING UROPLAKIN-POSITIVE CELLS IN PATIENTS WITH TRANSITIONAL CELL CARCINOMA OF THE BLADDER

Abstract

Uroplakin II is a highly specific marker for human TCC and the detection of uroplakin II in the peripheral blood is associated with metastatic spread of bladder cancer cells. The specific and sensitive detection of uroplakin II provides a useful adjunct for detecting bladder cancer metastasis, staging, and monitoring chemotherapeutic response.