Spectroscopic Characterization and Biological Potential of Palladium(II) Complexes of Benzylidenehydrazinecarboxamide or -carbothioamide

Abstract

Abstract In this article a brief account of the synthesis, stereochemistry, and biochemical behavior of palladium(II) complexes of benzylidenehydrazinecarboxamide or -carbothioamide is presented. The bimolar addition and substitution products have been characterized by elemental analyses, conductance measurements, molecular-weight determinations, magnetic susceptibilities, and spectral studies viz., IR, 1H NMR, 19F NMR, and UV. The data support the binding of sulfur or oxygen and nitrogen to the palladium in and (X is O or S) types of complexes. The square-planar geometry has been proposed. The representative free ligands () and their respective metal complexes were tested in vitro against a number of microorganisms to assess their antimicrobial properties and in vivo to test their sterilizing potential. The results are indeed positive.