Bulletin of the Chemical Society of Japan · 1986 · 70 citations · 3 references
Natural SciencesChemistryOrganic ChemistryHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisIndole ChemistryIndole DerivativesIndole SynthesisKetones
Abstract In the presence of palladium(II) chloride, 2-bromoanilines readily react with the methyl vinyl ketone and the ethyl acrylate to produce vinylogous arylamino ketones and esters. A palladium(0)-assisted cyclization of the arylamino ketones and the esters leads to a formation of 3-substituted indoles.
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