Synthesis of New 8-Formyl-4-methyl-7-hydroxy Coumarin Derivatives

Abstract

8-Formyl-4-Methyl-7-Hydroxy Coumarin Derivatives were synthesized via Penchem condensation followed by Duffs reaction. Treatment of this with N,N-di substituted cyano acetamides in the presence of piperdine afforded New 8-Formyl-4-Methyl-7-Hydroxy Coumarin Derivatives (7a-o). Their structures were characterized by IR, <TEX>$^1H$</TEX> and <TEX>$^{13}C$</TEX> NMR and Mass spectral and elemental analysis data.