USE OF COUNTERCURRENT CHROMATOGRAPHY (CCC) TO SEPARATE MIXTURES OF ARTEMISININ, ARTEMISITENE, AND ARTEANNUIN B

Abstract

A series of solvent systems was developed for CCC to separate mixtures containing variable amounts of artemisinin, artemi-sitene, and arteannuin B. To purify multigram quantities of artemisinin by CCC it was necessary to maximize the amount of a mixture that could be dissolved in a fixed quantity of the solvent mixture.